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Corks popped, beats boomed out and giddy revelers rushed onto dancefloors when England’s nightclubs reopened Monday as the country lifted most remaining restrictions after more than a year of lockdowns, mask mandates and other pandemic-related curbs on freedom.

For clubbers and nightclub owners, the moment lived up to its media-given moniker, “Freedom Day.” But the big step out of lockdown was met with nervousness by many Britons, and concern from scientists, who say the U.K. is entering uncharted waters by opening up when infections are not falling but soaring.

As of Monday, face masks are no longer legally required in England, and with social distancing rules shelved, there are no limits on the number of people attending theater performances or big events.

For nightclubs, this is the first time they have been allowed to open in almost 18 months, and from London to Liverpool, thousands of people danced the night away at “Freedom Day” parties starting at midnight.

“It’s a most joyous occasion,” said Mark Troy, who went to The Piano Works club in London. “I love dancing and all my friend circle loves dancing and we haven’t been able to do it for one and a half years approximately so we are really excited about it.”

The venue’s social media marketing manager, Katie Moorhouse, said people were yearning to “have a good boogie again.”

But while entertainment businesses and ravers are jubilant, many others are deeply worried about the British government’s decision to scrap restrictions at a time when COVID-19 cases are on a rapid upswing due to the highly infectious delta variant first identified in India. Cases topped 50,000 per day last week for the first time since January, although virus deaths remain comparatively low so far.

Prime Minister Boris Johnson, who has dialed down talk of freedom in recent weeks, urged the public to exercise “prudence and respect for other people and the risks that the disease continues to present.”

In a reminder of how volatile the situation is, the prime minister was spending “freedom day” in quarantine. Johnson and Treasury chief Rishi Sunak are both self-isolating for 10 days after contact with Health Secretary Sajid Javid, who tested positive for COVID-19 on Saturday.

They are among hundreds of thousands of Britons who have been told to quarantine because they have been near someone who tested positive. The situation is causing staff shortages for businesses including restaurants, car manufacturers and public transport.

Globally, the World Health Organization says cases and deaths are climbing after a period of decline, spurred by the more contagious delta variant first identified in India. Like the U.K., Israel and the Netherlands both opened up widely after vaccinating most of their people, but had to reimpose some restrictions after new infection surges. The Dutch prime minister admitted that lifting restrictions too early “was a mistake.”

In the U.S., many areas abandoned face coverings when the Centers for Disease Control and Prevention said fully vaccinated people don’t need to wear them in most settings. Some states and cities are trying to decide what to do as cases rise again.

British officials have repeatedly expressed confidence that the U.K.’s country’s vaccine rollout — 68.3% of adults, or just over half of the total population, has received two doses — will keep the threat to public health at bay. But leading international scientists described England’s “Freedom Day” as a threat to the whole world, and 1,200 scientists backed a letter to British medical journal The Lancet that criticized the Conservative government’s decision.

“I can’t think of any realistic good scenario to come out of this strategy, I’m afraid,” said Julian Tang, a clinical virologist at the University of Leicester. “I think it’s really a degree of how bad it’s going to be.”

Tang said nightclubs in particular are potent spreading grounds. He said their core customer base — people 18 to 25 — is “not fully vaccinated. They’re not masking. They’re in very close contact, heavily breathing, shouting very loudly to the music, dancing with different people.”

“That’s the perfect mixing vessel for the virus to spread and to even generate new variants,” he said.

The government wants nightclubs and other crowded venues to check whether customers have been vaccinated, have a negative test result or have recovered from the disease.

There is no legal requirement for them to do so, however, and most say they won’t. Michael Kill, chief executive of the Night Time Industries Association, said many owners see the passes as a huge turn-off for customers and accuse the government of “passing the buck” to businesses.

“Either mandate it or don’t mandate it,” Kill said. “This is putting an inordinate amount of pressure on us.”

Johnson’s decision to scrap the legal requirement for face masks in indoor public spaces has also sowed confusion. Days after the prime minister said masks would still be “expected and recommended” in crowded indoor places but not compulsory, London Mayor Sadiq Khan announced that passengers on the capital’s subways and buses must continue to wear them.

Some retailers, like the bookstore chain Waterstones, said they would encourage customers to keep their masks on. But many believe implementing such policies will be tricky without the backing of the law.

The end of restrictions in England on Monday is a critical moment in Britain’s handling of the pandemic, which has killed more than 128,000 people nationwide, the highest death toll in Europe after Russia. Other parts of the U.K. — Scotland, Wales and Northern Ireland — are taking slightly more cautious steps out of lockdown.

Salsa instructor Esther Alvero is one of the many who say they’re excited but fearful. A co-founder of Cubaneando, a company that ran salsa club nights, classes and performances for gala events before the pandemic, Alvero says she has had next to no income in the past year. Her savings are gone and her dancers have had to survive by taking part-time jobs as cleaners or Amazon delivery drivers.

“I’m scared but we have to survive,” she added. “We have no option because the economic consequences could be worse than COVID itself.”

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